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Ocean Oxygen Levels And The Future Of Fish | Earth Wise

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Climate change is creating a cascade of effects in the world’s oceans.  Not only are ocean temperatures on the rise, but oceans are becoming more acidic, and oxygen deprived.  The warming temperatures and acidification have grabbed headlines and prompted academic research. Declining oxygen levels have not garnered as much attention.  But they spell bad news for fish.

Oxygen levels in the world’s oceans have dropped over 2% between 1960 and 2010 and are expected to decline up to 7% over the next century.  There are places in the northeast Pacific that have lost more than 15% of their oxygen.  There are a growing number of “oxygen minimum zones” where big fish cannot survive but jellyfish can.

Oceans are losing oxygen for several reasons.  First, warmer water can hold less dissolved gas than colder water.  (This is why warm soda is flatter than cold soda.)  Deeper in the ocean, oxygen levels are governed by currents that mix oxygen-rich surface water from above.  Melting ice in the warming polar regions add fresh, less-dense water that resists downward mixing in key regions.  Finally, increasing amounts of ocean bacteria in warming waters gobble up oxygen creating dead zones in the ocean.

In many places, fish species that cannot cope with lower oxygen levels are migrating from their usual homes, resulting in a decline in species diversity.  Our future oceans – warmer and oxygen-deprived – will not only hold fewer kinds of fish, but also smaller fish and even more greenhouse-gas producing bacteria.   

Climate change is bad news for fish and for the more than 3 billion people in the world who depend on seafood as a significant source of protein.

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As Ocean Oxygen Levels Dip, Fish Face an Uncertain Future

Photo, posted January 10, 2022, courtesy of Willy Goldsmith via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio

Antibiotics In Animal Agriculture | Earth Wise

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In animal agriculture, farmers use antibiotics to treat, prevent, and control animal diseases, and to increase the productivity of their operations.  According to the FDA, approximately 80% of all antibiotics sold in the U.S. are purchased for use in food-producing animals. 

The routine administration of antibiotics to farm animals for non-therapeutic purposes promotes the development of antibiotic-resistant bacteria, with repercussions for human and animal health.  As antibiotic-resistant bacteria spreads, medicines used to treat human diseases can become less effective. 

According to a new study led by researchers from the University of Washington, a California policy restricting the use of antibiotics in farm animals is associated with a reduction in one type of antibiotic-resistant infection in people in the state.  The findings, recently published in the journal Environmental Health Perspectives, suggest that regulations limiting the use of antibiotics in livestock can significantly impact human health. 

In 2018, California Senate Bill 27 banned routine preventive use of antibiotics in food-animal production and any antibiotic use without a veterinarian’s prescription.  Last year, the European Union passed a law restricting antibiotic use to only sick animals on farms.  And coming this June, most antibiotics – those that are medically important to humans and animals – will be by prescription only in the United States.  

Despite these changes, antibiotic resistance is projected to remain one of the biggest threats to human health over the next 50 years because resistance continues to grow and few new antibiotics are coming online. 

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Restricting antibiotics for livestock could limit spread of antibiotic-resistant infections in people

Ranchers should prepare now for 2023 animal antibiotic guidelines

Photo, posted May 8, 2018, courtesy of Preston Keres / USDA via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio

Turning Plastic Into Protein | Earth Wise

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Our planet is choking on plastic.  According to the United Nations, 79% of the 6.3 billion tons of plastic produced every year accumulates in landfills.  Half of all plastic produced is actually designed to be used just once and thrown away.  But plastic is not only accumulating on land.  In fact, the world’s oceans are projected to contain more plastic by weight than fish by the year 2050.     

According to new research, solving the plastic waste issue could help address another prominent global issue: hunger.  A multidisciplinary team of engineers, chemists, and biologists led by researchers from Michigan Tech University has developed a process to break plastics down to be recycled into useful products, including edible protein powder.

The research team’s process converts plastic into compounds using heat and a reactor that deconstructs the material’s polymer chains. The oil-like substance is then fed to a community of oil-eating bacteria.  The bacteria grow rapidly on the oily diet, producing more bacterial cells composed of roughly 55% protein.  This majority-protein byproduct is then dried out and turned into an edible powder.   The end result doesn’t look like plastic at all.  In fact, it resembles a yeast byproduct that comes from brewing beer. 

This research is funded by an award from the US Department of Defense.  The DoD often deploys soldiers in areas where access to food is challenging.  Converting plastic to protein could be part of a solution to that problem. 

While eating something that began as plastic might take some getting used to, it could be part of the solution to both plastic pollution and global hunger.

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Turning Trash Into Treasure: The Plastic to Protein Powder Solution

Beat Plastic Pollution

Photo, posted February 2, 2022, courtesy of Ivan Radic via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio

Electricity From Bacteria | Earth Wise

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Microbiologists at Radboud University in the Netherlands have demonstrated in the laboratory that methane-consuming bacteria can generate electrical power.  Their study was recently published in the journal Frontiers in Microbiology.

The bacteria studied is called Candidatus Methanoperedens and in the natural environment it consumes methane in water sources that are contaminated with nitrogen including places like water-filled ditches and some lakes. The bacteria in the study make use of the nitrates in the water to break down and digest the methane. Methanogens, which are bacteria that reduce carbon dioxide to form methane, are the source of the methane in these places. 

The researchers exploited these complex interactions of bacteria to create a source of electrical power that is essentially a kind of battery with two terminals.  One of the terminals is a chemical terminal and one is a biological terminal.  They grew the bacteria on one of the electrodes where the bacteria donate electrons that result from its conversion of methane.  (Other microbiologists at the same institution had previously demonstrated electrical generation from a similar battery containing anammox bacteria that use ammonium rather than methane in their metabolic processing).

In the study, the Radboud scientists managed to convert 31% of the methane in the water into electricity but they are aiming at higher efficiencies. 

This approach represents a potential alternative to conventional biogas electricity generation.  In those installations, methane is produced by microorganisms digesting plant materials and the methane is subsequently burned to drive a turbine to generate power.  Those systems in fact have an efficiency of less than 50%.  The researchers want to determine whether microorganisms can do a better job of generating electricity from biological sources than combustion and turbines can do.

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Bacteria generate electricity from methane

Photo, posted December 3, 2008, courtesy of Martin Sutherland via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

Dangers Of Thawing Permafrost | Earth Wise

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The thawing of the permafrost in the Arctic is a major concern from the standpoint of the potential release of enormous amounts of carbon dioxide trapped in it.  There are nearly 2,000 billion tons of carbon there, which is as much as humanity releases into the atmosphere in 50 years.  But greenhouse gases are not the only danger posed by permafrost thawing.  There are also microbes, unknown viruses, and chemicals that could be very dangerous.

More than 100 diverse microorganisms in Siberia’s deep permafrost have been found to be antibiotic resistant.  The deep permafrost is one of the few environments on Earth that have not been exposed to modern antibiotics.  As the permafrost thaws, its bacteria could mix with meltwater and create new antibiotic-resistant strains.

By-products of fossil fuels – introduced into permafrost environments since the beginning of the industrial revolution – are present.  Metal deposits including arsenic, mercury, and nickel, have been mined for decades and have contaminated large areas.

Now-banned pollutants and chemicals – including DDT – came to the Arctic through the atmosphere and over time have become trapped in the permafrost.

There is now ongoing research further characterizing the microbes frozen in permafrost and providing more precise measurement of emissions hotspots in permafrost regions.  Scientists are increasingly turning to integrated Earth observations from the ground, the air, and space.

There are models that predict the gradual release of emissions from permafrost over the next century.  Other models say it could happen within just a few years.  The worst-case scenario would be utterly catastrophic but none of the scenarios portend anything good.

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Thawing Permafrost Could Leach Microbes, Chemicals Into Environment

Photo, posted February 9, 2017, courtesy of Benjamin Jones/USGS via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

Plastic-Eating Bugs | Earth Wise

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27-year-old Miley Cyrus and 30-year-old Liam Hemsworth divorced exactly one year ago, but still continue to remember each other quite often in conversations with reporters. Recently, Miley indulged in nostalgia once again. During a recording Miley Cyrus boyfriend list of the podcast Barstool Call Her Daddy, the singer said that her ex-husband was her first man. It happened almost 10 years before they got married. I didn’t have that with men until I was 16, but I ended up marrying this guy,

According to a new study, microbes in oceans and soils around the world are evolving to eat plastic.  The study by Chalmers University in Sweden was published recently in the journal Microbial Ecology.

The study is the first large-scale assessment of the plastic-degrading potential of bacteria.  There are 95 microbial enzymes already known to degrade plastic. 

The researchers looked for similar enzymes in environmental DNA samples taken from bacteria from 236 different locations around the world. They found that one in four of the organisms analyzed carried suitable enzymes.  Overall, they found many thousands of new enzymes.

The explosion of plastic production in the past 70 years has given microbes time to evolve to make use of plastic.  About 12,000 new enzymes were found in ocean samples and 18,000 in soil samples.  Nearly 60% of the new enzymes did not fit into any known enzyme classes, suggesting that these molecules degrade plastics in ways that were previously unknown.  The large number of enzymes in such a wide range of habitats is an indication of the scale of the problem of plastics in the environment.

The first bacterium that eats plastic was discovered in a Japanese waste dump in 2016.  Scientists tweaked that microbe in 2018 and managed to create an enzyme that was even better at breaking down plastic bottles.

The next step in research is to test the most promising enzyme candidates in the laboratory to investigate their properties and see how effective they can be in plastic degradation.  The hope is to be able to engineer microbial communities with targeted degrading functions for specific polymer types.

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Bugs across globe are evolving to eat plastic, study finds

Photo, posted June 19, 2013, courtesy of Alan Levine via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

Capturing Methane To Feed Fish | Earth Wise

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Methane in the atmosphere is an extremely potent greenhouse gas.  Its warming potential is about 85 times that of carbon dioxide over a 20-year period.  It also worsens air quality by increasing atmospheric ozone.  Many human activities add methane to the atmosphere, notably emissions from landfills and oil and gas facilities.

Capturing methane from these sources for subsequent use is currently uneconomical but new research from Stanford University analyzes the market for using the methane to feed bacteria to produce fishmeal.

Methane-consuming bacteria called methanotrophs can be grown in chilled, water-filled bioreactors containing pressurized methane, oxygen, and nutrients.  The bacteria produce a protein-rich biomass that can be used as fishmeal in aquaculture.  This could offset demand for fishmeal made from small fish or plant-based feeds that require land, water, and fertilizer.

Some companies already do this using natural gas provided by utility pipelines, but it would be far better for the environment to use methane emitted at large landfills, wastewater treatment plants, and oil and gas facilities.

Consumption of seafood has more than quadrupled since 1960, depleting wild fish stocks.  Farmed fish now provide half of all the animal-sourced seafood we eat.

The Stanford research analyzed the cost of methanotrophic fishmeal production under various scenarios and found it to be very competitive with and in some cases considerably cheaper than current market prices for fishmeal. 

According to the study, this process could profitably supply total global demand for fishmeal with methane captured in the U.S. alone.

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Stanford researchers reveal how to turn a global warming liability into a profitable food security solution

Photo, posted April 30, 2017, courtesy of Artur Rydzewski via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

Could Lyme Disease Be Eradicated? | Earth Wise

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Tiny ticks are a big problem.  Measuring only three to five millimeters in size, ticks are widely distributed around the world.  They are external parasites, feasting on the blood of birds, reptiles, amphibians, and mammals – including humans.

According to estimates from the Centers for Disease Control and Prevention, ticks infect an estimated 476,000 people with Lyme disease in the United States every year.  Lyme disease is caused by a bacterium called Borrelia burgdorferi that lurks in wild mice. Ticks that feed on the mice become infected and can then in turn infect people and animals.   

The disease is not only a problem in the United States, but in other parts of North America, Europe and Asia as well.  It often causes a characteristic “bullseye” rash and flu-like symptoms. If left untreated, it can lead to serious long-term health problems.

Currently, lyme disease is treated using antibiotics.  But antibiotics kill a wide range of bacteria – including healthy gut bacteria – which can lead to additional health issues and more antibiotic resistance.

A recent discovery by researchers from Northeastern University in Boston could allow Lyme disease to be eradicated in the wild.  The researchers found that a compound called hygromycin A is deadly to the bacterium that causes Lyme disease but harmless to animals and has little effect on most other bacteria. 

The little-known antibiotic cleared Lyme disease infection in mice, both when administered via injection and when ingested using bait.  As a result, dropping feeding baits could eradicate Lyme disease from whole areas or even entire countries.  The first field trial will be next summer.

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Drug treatment for Lyme disease could lead to its eradication

Photo, posted June 21, 2017, courtesy of NIAID via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

Cleaning Up Diesel With Bacteria | Earth Wise

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Mothballed military outposts with piles of rusting oil drums are not an unusual sight in Greenland.  There are about 30 abandoned military installations in Greenland and diesel that was once used to operate generators and other machinery has, in many cases, seeped into the ground.

Removing tons of contaminated soil from these sites is incredibly resource-intensive involving the use of aircraft and ships, so it has not really been practical.  As a result, Danish Defense and the engineering company NIRAS instead conducted a five-year experiment to optimize the conditions for naturally occurring soil bacteria to break down the contaminating diesel.

The experiment was performed at Station 9117 Mestersvig, an abandoned military airfield on the coast of East Greenland.  Forty tons of diesel fuel contaminated the soil there.

The remediation method using bacteria is known as landfarming and has most often been applied in warmer climates around the world.  This was the first large-scale test under Arctic conditions.

Landfarming works by distributing contaminated soil in a thin layer, which is then plowed, fertilized, and oxygenated every year to optimize conditions for bacteria to degrade hydrocarbons.

The site was monitored by scientists from the University of Copenhagen, and they found that after five years, the bacteria had bioremediated as much as 82 percent of the 5,000 tons of contaminated soil on the site. 

Based on these results, it appears to be feasible for naturally occurring bacteria to be used to remediate contamination in all of the 30 deserted military installations in Greenland as well as in other Arctic sites contaminated by diesel pollution.

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Bacteria used to clean diesel-polluted soil in Greenland

Photo, posted September 6, 2013, courtesy of Maj. Matthew J. Sala/The U.S. Air National Guard via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

Helping Corals With Beneficial Bacteria | Earth Wise

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A group of researchers at the King Abdullah University of Science and Technology in Saudi Arabia is exploring a novel technology to improve the health of corals.  Around the globe, corals are being stressed by pathogens, toxins, and warming waters leading to widespread bleaching events.

The new idea is to introduce beneficial bacteria to the corals, thereby boosting the strength and resilience of their symbiotic partners.  The concept is akin to the use of probiotics in plant science.  Corals rely on bacterial and algal symbionts to provide nutrients, energy (through photosynthesis), toxin regulation, and protection against pathogens.  

The researchers selected bacteria that are naturally symbiotic to specific coral species on reefs in the Red Sea, ensuring that no alien bacteria are accidentally introduced.  A probiotic cocktail comprising six bacteria strains was used in a laboratory setting.  Results in the lab have been promising so far, as they have observed dynamic and metabolic alterations to the corals that boosted their chances of survival under heat stress. 

Success in the lab will need to be translated to success in the open oceans, which is challenging.  Scaling up and seeding whole reefs might involve robots and artificial intelligence in order to deliver probiotics either into sediments or directly onto corals.

The use of beneficial microorganisms is not the solution to the global destruction of coral reefs.  Only worldwide CO2 mitigation can ultimately accomplish that.  But the probiotic approach might buy corals some time as they deal with shifting environmental pressures and try to adapt to a changing world.

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Microbiome boost may help corals resist bleaching

Photo, posted March 18, 2018, courtesy of Steven dos Remedios via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

Turning Food Waste Back Into Food | Earth Wise

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Scientists at the University of California Riverside have discovered that fermented food waste can boost bacteria that increase crop growth, make plants more resistant to pathogens, and reduce the carbon emissions resulting from farming.

Food waste is a serious problem from multiple perspectives.  As much as 50% of food is thrown away in the United States and most of that simply ends up in landfills, taking up more than 20% of America’s landfill volume.  Food waste is a huge economic loss as well as a significant waste of freshwater resources used to produce food.

The researchers studied byproducts from two kinds of food waste readily available in Southern California:  beer mash – a byproduct of beer production – and mixed food waste discarded by grocery stores.

Both types of waste were fermented and then added to the irrigation system watering citrus plants in a greenhouse.  Within 24 hours, the average population of beneficial bacteria was two to three orders of magnitude greater than in plants that did not receive the treatments. This led to improvements in the carbon to nitrogen ratio in crops.  When there are enough so-called good bacteria in plants, they produce antimicrobial compounds and metabolites that help plants grow better and faster.

The results of the study suggest that the use of food waste products in agriculture is beneficial and could complement the use of synthetic chemical additives by farmers, perhaps eliminating it entirely.  Crops would in turn become less expensive.

Making use of food waste in agriculture is a step towards a more circular economy in which we use something and then find a new purpose for it.

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Turning food waste back into food

Photo, posted October 28, 2012, courtesy of Daniel Lobo via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

A New Super-Enzyme For Breaking Down Plastic | Earth Wise

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The problems caused by plastic waste continue to grow.  Plastic pollution is everywhere, from the Arctic to the depths of the ocean.  We consume microplastics in our food and breathe them in the air.  It is very difficult to break down plastic bottles into their chemical constituents in order to make new ones from old ones. Therefore, we continue to produce billions of single-use plastic bottles, creating more and more new plastic from oil each year. 

Scientists at the University of Portsmouth in the UK have developed a new super-enzyme that degrades plastic bottles six times faster than before.  They believe that the new enzyme could be used for plastic recycling within a year or two.

The super-enzyme was derived from bacteria that naturally have the ability to eat plastic.  The researchers engineered it by linking two separate enzymes, both of which were found in a plastic-eating bug discovered in a Japanese waste site in 2016.  They revealed an engineered version of the first enzyme in 2018, which started breaking down plastic in a few days.  They had the idea that connecting two enzymes together would speed up the breakdown of plastic.  Such linkage could not happen naturally in a bacterium. 

Carbios, a French company, announced a different enzyme in April that can degrade plastic bottles within 10 hours but requires heating above 160 degrees Fahrenheit.  The new super-enzyme works at room temperature.

The team is now examining how the enzymes can be tweaked to make them work even faster.  Meanwhile, they plan to work in partnership with companies like Carbios, to bring super-enzymes for breaking down plastics into commercial use.

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New Super-Enzyme Can Break Down Plastic at Rapid Pace

Photo, posted March 24, 2017, courtesy of the USFWS – Pacific Region via Flickr. Photo credit: Holly Richards/USFWS.

Earth Wise is a production of WAMC Northeast Public Radio.

Protecting Fresh Produce | Earth Wise

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Fresh fruits and vegetables can sometimes become contaminated by microorganisms during their long journey from fields to restaurants and grocery stores.  Contaminated produce can spoil other produce, which increases the number of fruits and vegetables in the supply chain that can cause illnesses. 

In order to prevent this cross-contamination between produce, researchers from Texas A&M University have designed a coating that can be applied to food-contact surfaces, like buckets, rollers, and conveyor belts.  The newly-created dual-function coating is both water-repellent and germicidal.  In other words, it can both repel and kill.  Without water, the researchers say bacteria can’t stick or multiply on surfaces, drastically reducing contamination.

To make this dual-function coating, the researchers chemically-attached a thin layer of silica to an aluminum sheet.  They then added a mixture of silica and lysozyme, a naturally-occurring germicidal protein found in egg whites and tears.  Together, the silica-aluminum and the silica-lysozyme formed microscopic bumps and crevices.  According to the research team, this rough texture, albeit microscopic, is the key to the coating’s superhydrophobic properties.  

The researchers tested the coating’s effectiveness at curbing the growth of two strains of disease-causing bacteria:  Salmonella and Listeria.  Upon review, the number of bacteria found on the dual-coating surfaces was 99.99% less than what was found on the uncoated surfaces. 

Despite the success in preventing bacterial spread, the research team said more research needs to be done to see how well the coating works for mitigating viral cross-contamination.  Since the coating would need to be reapplied after a certain amount of use, the researchers also plan to develop more permanent, dual-function coatings. 

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New dual-action coating keeps bacteria from cross-contaminating fresh produce

Photo, posted April 14, 2012, courtesy of U.S. Department of Agriculture via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

Methane-Eating Bacteria And Greenhouse Gas Emissions | Earth Wise

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One of the great concerns about the warming Arctic temperatures is that thawing permafrost will release alarming amounts of methane into the atmosphere.  Organic material in the permafrost begins to decompose when temperatures rise, and methane is released in the process.

Methane is a far more potent greenhouse gas than carbon dioxide.  Methane’s lifetime in the atmosphere is much shorter than carbon dioxide, but it is more efficient at trapping radiation.  Pound for pound, the comparative impact of methane is more than 25 times greater than carbon dioxide.

A new study, published by scientists at Purdue University, has discovered a type of methane-oxidizing bacteria living in upland Arctic soils that could potentially be reducing the amount of methane emitted by decomposing permafrost.

The findings of the research indicate that the net greenhouse gas emissions from the Arctic may be much smaller than previously modeled because of the increased productivity of a type of bacteria known as high affinity methanotrophs, or HAMs.  This group of bacteria uses atmospheric methane as an energy source.  The emissions from wetlands will potentially be very large, but the contribution from the uplands will be mitigated by the bacteria.

Organic-rich soils, including permafrost, comprise only 13% of the Arctic land area and are the major source of methane emissions.  The other 87% of the region is dominated by mineral-rich soils that support HAMs.  Because of this, overall methane emissions continue to be less than climate models have predicted.

While this is good news, the researchers warn that Arctic emissions overall will continue to increase as shown in other studies.

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Methane-Eating Bacteria Could Help Decrease Greenhouse Gas Emissions From Thawing Arctic Tundra

Photo, posted July 12, 2016, courtesy of Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

A Hidden Source Of Arctic Carbon | Earth Wise

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Researchers from the University of Texas at Austin, the U.S. Fish and Wildlife Service, and Florida State University have published a paper presenting evidence of significant and previously undetected concentrations and fluxes of dissolved organic matter entering Arctic coastal waters.  The source of the organic matter is groundwater flow atop the frozen permafrost.  The groundwater moves from land to sea unseen, but the new research reveals that it carries significant concentrations of carbon and other nutrients to Arctic coastal food webs.

Globally, groundwater is important for delivering carbon and other nutrients to oceans, but in the Arctic, where much water is trapped in the permafrost, its role was thought to be minimal.  But the new research reveals that groundwater may be contributing an amount of dissolved organic matter to the Alaskan Beaufort Sea that is comparable to what comes from neighboring rivers during the summer.

The researchers found that shallow groundwater flows beneath the surface and picks up new, young organic carbon and nitrogen, but it also mixes with layers of deeper soils and thawing permafrost, picking up and transporting century-to-millennia old organic carbon and nitrogen.  This material is unique because it is directly transported to the ocean without seeing or being photodegraded by sunlight and may be valuable as a food source to bacteria and higher organisms that live in Arctic coastal waters.

The study concluded that the supply of leachable organic carbon from groundwater amounts to as much as 70% of the dissolved organic matter that enters the Beaufort Sea from rivers during the summer.  The role that groundwater inputs play in Arctic coastal ecosystems will be an area of active research for years to come.

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Hidden Source of Carbon Found at the Arctic Coast

Photo, posted June 14, 2015, courtesy of Eugen Marculesco via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

A New Kind Of Antibiotic | Earth Wise

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Antimicrobial resistance is a serious and growing problem for public health.  Over time, more and more types of bacteria have become resistant to known antibiotics making it very difficult to treat various kinds of infections. 

A new group of antibiotics with a unique approach to attacking bacteria has been discovered at McMaster University in Canada, representing a promising new clinical approach in the fight against antimicrobial resistance. 

The newly found corbomycin and the lesser-known complestatin have a never-before-seen way to kill bacteria, namely, breaking the function of the bacterial cell wall. Bacteria have a wall around the outside of their cells that gives them shape and is a source of strength.  Antibiotics like penicillin kill bacteria by preventing building of the wall, but the new antibiotics work by doing the opposite – they prevent the wall from being broken down. Breaking down the cell wall is critical for cells to divide. In order for bacteria to grow and spread, they need to expand and divide. By completely blocking the breakdown of the wall, it is as if the bacterium is trapped in a prison and can’t expand or grow. 

The researchers demonstrated in mice that these new antibiotics can block infections caused by the drug resistant Staphylococcus aureus which is a group of bacteria that can cause many serious infections. 

The researchers believe this new approach can be applied to other antibiotics and lead to the discovery of new ones with different mechanisms of action. This study found one completely new antibiotic, but since then, they have found a few others in the same family that have this same new mechanism. 

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Antibiotics discovered that kill bacteria in a new way

Photo, posted March 15, 2012, courtesy of Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

Mexico’s Wonder Plant

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In 1979, an American naturalist named Thomas Hallberg visiting a small town in Oaxaca, Mexico was amazed to find a type of local maize – or corn – that grew nearly 20 feet high in poor-quality soil even though the local farmers did not use any fertilizer.

The unique corn plant had aerial roots that grew a mucous-like gel just before harvest season.  It seemed totally implausible, but the plant seemed to be fixing its own nitrogen:  extracting it from the air and somehow making it useful to the plant.

In 1992, Hallberg returned with a group of Mexican scientists and collected samples to study in his lab.  His research showed that the maize indeed received nitrogen from the air through its aerial roots.  It took over 20 years to figure out what was going on in the plants.  It turns out that bacteria that thrive in the low-oxygen environment of the maize’s mucus pulls nitrogen from the air and feeds it to the plant.

Scientists will probably spend years figuring out if a commercial application of this indigenous maize is viable.  It isn’t guaranteed that the self-fertilizing trait of the plant can be bred into a commercial crop.  But if it can, the payoff would be huge.  Farmers spend more than $3 billion a year on corn fertilizer in the US alone.

A vexing problem is who should reap the financial benefits of the maize.  The isolated village where the plant is grown has already signed an agreement to share in any such benefits.   But there are other Oaxacan villages that also grow the plant. 

Mexico’s wonder plant is likely to be caught up in the growing issue of biopiracy, which is the exploitation of indigenous knowledge and biological resources without permission.

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Indigenous Maize: Who Owns the Rights to Mexico’s ‘Wonder’ Plant?

Photo credit: ALLEN VAN DEYNZE/UC DAVIS

Earth Wise is a production of WAMC Northeast Public Radio.

Reducing Methane From Animals

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Methane emissions from ruminant livestock are currently estimated to be more than 100 million tons each year and, after rice agriculture, represent the biggest human-initiated methane source.  Given that fact, there is widespread encouragement for people to reduce their consumption of meat in order to reduce the amount of the potent greenhouse gas going into the atmosphere.

But an additional strategy to lower global methane emissions is to actually reduce the amount of methane produced by each animal.  To that end, researchers at the University of Otago in New Zealand have now identified new processes that control methane production in the stomachs of sheep and similar animals like cattle and deer.

They determined the specific microbes and enzymes that control the supply of hydrogen, which is the main energy source for methane producing microbes, known as methanogens.  Their work is focused on the development of small molecule inhibitors and vaccines to specifically target the production of methane by methanogens.  By reducing the supply of hydrogen to methanogens, it is possible to reduce animal methane emissions.

The research involved studying two types of sheep – those producing large amounts of methane and those producing less.  They found that the most active hydrogen-consuming microbes differed between the sheep.  Specifically, in the low methane emitting sheep, hydrogen consuming bacteria dominated over methanogens.

Ultimately, a strategy might emerge to introduce feed supplements that encourage non-methane producers to out-compete methanogens.  Controlling the supply of hydrogen to the methanogens will lead to reduced methane emissions. 

Having low-emission cattle would definitely help reduce the impact of agriculture on the climate.

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Scientists discover processes to lower methane emissions from animals

Photo, posted April 7, 2017, courtesy of Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

Controlling Malaria Without Chemicals

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Nearly half of the world’s population lives in areas vulnerable to malaria.  The disease kills roughly 450,000 people each year, most of them children and pregnant women.  Malaria is spread by Anopheles mosquitoes and, over time, the mosquitoes have been developing resistance to the chemical insecticides that are used to control them.  In addition, there is great concern about the toxic side effects of the chemicals used on the mosquitoes.

About 30 years ago, scientists identified a type of bacteria that kills Anopheles, but the mechanism was not understood.  As a result, the bacteria could not be replicated or used as an alternative to chemical insecticides.

But now, an international research team, headed by researchers at UC Riverside, has identified the neurotoxin produced by the bacteria and has determined how it kills Anopheles.  The work is described in a paper published in Nature Communications.

It took the team 10 years to achieve a breakthrough in understanding the bacteria.  Modern gene sequencing techniques were the key.

While many neurotoxins target vertebrates and are highly toxic to humans, the neurotoxin that kills Anopheles mosquitoes does not affect humans, vertebrates, fish, or even other insects.  Known as PMP1, the substance is not even toxic to mice when given by direct injection.

The team has applied for a patent on this discovery and hopes to find partners to help them develop the bacteria-based insecticide.

There is a high likelihood that PMP1 actually evolved to kill the Anopheles mosquito.  This finding opens the door to new avenues of research into other environmentally friendly insecticides that would be targeted at other disease-spreading pests.

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Controlling deadly malaria without chemicals

Photo, posted June 9, 2018, courtesy of Mario Yardanov via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

Drugs In The Water

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According to a new study published in the journal Environmental Research Letters, concentrations of pharmaceuticals in rivers and lakes have dramatically increased across the globe over the past 20 years.

Traces of medicines get passed into waterways through the excretion of active drugs in human waste, the disposal of unused medicines down drains, and runoff from livestock farms.

The study looked in detail at two specific drugs:   carbamazepine, an anti-epileptic drug, and ciprofloxacin, an antibiotic.   The study found that the risk of ecological damage from the residue from these two drugs was 10 to 20 times higher in 2015 than in 1995.

Chronic exposure to carbamazepine, for example, has been shown to alter feeding behavior and reduce egg viability in zebrafish, as well as reduce reproductive success in crustaceans.  Antibiotics can alter major nutrient cycles and decrease the effectiveness of bacteria-based wastewater treatment systems.

The study, led by researchers from the Netherlands, created a new model estimating concentrations of the two drugs over a 20-year period in 449 aquatic systems around the globe.  The model predicts a relatively high environmental risk in densely populated and dry areas such as the Middle East. 

When the researchers compared the model’s results to samples from four river systems in various locations, they found that the actual drug concentrations were even higher than model results, in some cases by a factor of 10 to 100. 

The new model should act as a guide for a more thorough investigation into pharmaceutical residues in waterways, which pose significant environmental risks all over the world.

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Concentrations of Pharmaceuticals in Freshwater Increasingly Globally

Photo, posted March 22, 2012, courtesy of Rajeev Rajagopalan via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

WAMC Northeast Public Radio

WAMC/Northeast Public Radio is a regional public radio network serving parts of seven northeastern states (more...)