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medicine

RNA Modification For Plants | Earth Wise

September 8, 2021 By EarthWise Leave a Comment

Manipulating RNA can lead to huge increases in crop yields

We have heard a lot about RNA this past year as messenger RNA vaccine technology has been used for the first time to combat the Covid-19 pandemic.  Now RNA-based technology has shown promise to make major contributions to agriculture.

A group of researchers at the University of Chicago and two Chinese universities have announced that manipulating RNA can allow plants to yield dramatically more crops as well as have better drought resistance.

Adding  gene encoding for a protein called FTO to both rice and potato plants increased their yield by 50% in initial field tests.  The plants were larger, produced longer root systems, and could better tolerate drought conditions.  Further analysis showed that the plants had increased their rate of photosynthesis.

FTO protein erases chemical marks on RNA.  Specifically, it controls a process known as m6A, which is a key modification of RNA.  The FTO erases m6A to reduce some of the signals that tell plants to slow down and reduce growth.  Plants modified with the addition of FTO produced significantly more RNA than control plants.

Experiments with both rice plants and potato plants – which are completely unrelated – demonstrated the same results, indicating that the technique could be broadly applicable.  (The genetic modification is rather simple to make and has worked with every type of plant the researchers have tried it with so far).

These results are just the beginning but demonstrate the potential of a technology that could help address problems of poverty and food insecurity at a global scale as well as responding to climate change.  The world depends on plants for everything from wood, food, and medicine, to flowers and oils. This technique has the potential to dramatically increase the stock material we can get from most plants.

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RNA breakthrough creates crops that can grow 50% more potatoes, rice

Photo, posted September 22, 2014, courtesy of Toshiyuki Imai via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

Permanent Time Observation | Earth Wise

September 25, 2020 By EarthWise Leave a Comment

permanent standard time

Americans have debated the value of daylight savings time going all the way back to Benjamin Franklin.  As a country, we adopted the practice of changing our clocks twice a year in 1918.

Since the energy crisis of the 1970s, there have been a number of initiatives aimed at making daylight savings time permanent.  However, there is also a growing movement to eliminate the practice entirely.

In August, the American Academy of Sleep Medicine published a position statement calling for the abolishing of daylight savings time in favor of fixed, national, year-round standard time.

The statement describes the adverse effects of the annual abrupt switch to daylight savings time, which range from increased risk of stroke and hospital admissions to sleep loss and increased production of inflammatory markers, which are one of the body’s responses to stress.  It also cites studies that show that traffic fatalities increase by as much as six percent in the first few days following the change to daylight savings time.  Other research shows that there is an 18% increase in adverse medical events related to human error in the week after switching to daylight savings time.

In July, a survey by the academy of more than 2,000 U.S. adults found that 63% support the elimination of seasonal time changes in favor of a national, fixed year-round time, and only 11% oppose the idea, but many of those in favor of the idea actually want permanent daylight savings time.

The sleep academy contends that permanent standard time is the best choice to most closely match our circadian sleep-wake cycle while daylight saving time results in more darkness in the morning and more light in the evening, disrupting the body’s natural rhythm.

Residents of Arizona and Hawaii get to sit out this debate since they don’t change their clocks.

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American Academy of Sleep Medicine calls for elimination of daylight saving time

Photo, posted May 28, 2018, courtesy of Kis Akos via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

An Environmental Victory In Cameroon | Earth Wise

September 23, 2020 By EarthWise Leave a Comment

Preserving biodiversity in Cameroon

The Ebo Forest in Cameroon is one of the last intact forests in central Africa and is a biodiversity hotspot, home to hundreds of rare plants and animal species, including tool-using Nigeria-Cameroon chimpanzees, western gorillas, forest elephants, red colobus monkeys, and giant goliath frogs.  The 600 square miles of mountain slopes and river valleys are covered by thick tree canopies that shelter a fascinating array of species.

This past July, Cameroon Prime Minister Joseph Dion Ngute signed a decree that turned half of the Ebo Forest into a so-called forest management unit, meaning that the government could begin to sell logging concessions.

However, on August 11, Ngute, at the direction of President Paul Biya, withdrew the decree, suspending any logging plans.  President Biya also ordered a delay to reclassify an additional 160,000 acres of the Ebo, which might have opened up even more forest for logging.

Apart from its rich biodiversity, the Ebo Forest is culturally and societally important for the Banen Indigenous people, who consider it to be their sacred ancestral home.  The Banen were ousted from the forest in the 1960s but took up settlements just a few miles from its borders.  They still rely on the forest for food and medicines.  Meanwhile, the proximity of the forest to big cities makes it an easy target for bushmeat poachers.

Both conservation groups and indigenous leaders welcomed the withdrawal of the decree but remain concerned about the future of the Ebo Forest.  Conservation groups hope that the international community will seize the opportunity to work with the government of Cameroon to make the Ebo Forest a permanent showcase for long-term conservation in harmony with very challenged communities.

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Cameroon Cancels Plan to Log Half of the Ebo Forest, a Key Biodiversity Hotspot in Central Africa

Photo, posted September 17, 2005, courtesy of Salva le Foreste via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

Chocolate Is Good For The Heart | Earth Wise

August 27, 2020 By EarthWise Leave a Comment

chocolate is healthy

At last a good news story about what we eat, or more specifically, about what we like to eat.   According to research published recently in the European Journal of Preventive Cardiology, eating chocolate at least once a week is linked with a reduced risk of heart disease.

In the past, clinical studies have shown that chocolate is beneficial for both blood pressure and the lining of blood vessels.   The new study suggests that chocolate helps to keep the heart’s blood vessels healthy.

The researchers conducted a combined analysis of studies from the past five decades examining the association between chocolate consumption and coronary artery disease.  The analysis included data from over 300,000 participants who reported their chocolate consumption.  About 14,000 participants in the study ultimately developed coronary heart disease.  Compared with consuming chocolate less than once a week, eating chocolate more than once a week was associated with an 8% decreased risk of coronary heart disease.

Chocolate contains heart-healthy nutrients such as flavonoids, methylxanthines, polyphenols, and steric acid.  These substances may reduce inflammation and increase good (HDL) cholesterol.

The study did not examine whether any particular type of chocolate is more beneficial or whether there is an ideal portion size.  So, while chocolate appears to be promising for reducing the occurrence of coronary heart disease, it will require more research to determine how much and what kind of chocolate could be recommended.

Not to be spoilsports, but the doctors who conducted the study warned against overeating.  Eating large quantities of chocolate products laden with calories, sugar, milk and fat, is not a recommended path to improved health.

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Chocolate is good for the heart

Photo, posted February 22, 2014, courtesy of Jan David Hanrath via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio.

Tiger Poaching

February 14, 2017 By EarthWise

https://earthwiseradio.org/wp-content/uploads/2017/02/EW-02-14-17-Tiger-Poaching-on-the-Rise.mp3

Last year, tiger poaching in India jumped to its highest levels in 15 years.   The spike was the result of killings by gangs of poachers, tigers being snared by locals trying to trap other animals for food, and by cutbacks in anti-poaching efforts because of budget cuts.

[Read more…] about Tiger Poaching

Livestock And Antibiotics

January 19, 2017 By EarthWise

https://earthwiseradio.org/wp-content/uploads/2017/01/EW-01-19-17-Livestock-and-Antibiotics.mp3

According to the FDA, approximately three-quarters of all antibiotics used in the U.S. are fed to livestock for non-therapeutic purposes.  This routine administration of antibiotics promotes the development of antibiotic-resistant bacteria, which can spread to animals and humans.   And as antibiotic-resistant bacteria spreads, medicines used to treat human diseases can become less effective. Antibiotic resistant infections kill 90,000 Americans each year.

[Read more…] about Livestock And Antibiotics

The Threat Of Bushmeat Hunting

November 22, 2016 By WAMC WEB

https://earthwiseradio.org/wp-content/uploads/2016/11/EW-11-22-16-The-Threat-of-Bushmeat-Hunting.mp3

A recent study has identified the steep decline of more than 300 species of mammals as a result of unregulated or illegal hunting.  Humans are consuming many of the world’s wild mammals to the point of extinction.

[Read more…] about The Threat Of Bushmeat Hunting

Help For Pangolins

November 3, 2016 By WAMC WEB

https://earthwiseradio.org/wp-content/uploads/2016/10/EW-11-03-16-Help-for-Pangolins.mp3

Poaching and illegal trafficking in exotic animals is a world-wide problem that most of us are aware of.  What most of us are less aware of is that the most trafficked mammal in the world is the pangolin, which you may well have never even heard of.

[Read more…] about Help For Pangolins

Antibiotic Apocalypse

December 18, 2015 By WAMC WEB

https://earthwiseradio.org/wp-content/uploads/2015/12/EW-12-18-15-Antibiotic-Apocalypse.mp3

Virtually everyone listening to this radio segment has relied on antibiotics to treat a bacterial infection. Since the 1940’s, we’ve used antibiotics to combat everything from strep throat to sinus infections. They also play an important role in surgery and cancer therapies.

[Read more…] about Antibiotic Apocalypse

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