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Cryo Conservation | Earth Wise

August 2, 2023 By EarthWise Leave a Comment

Recent studies have shown that there has been a 69% decline in global animal populations since 1970.  There is a biodiversity crisis in the world.  In the face of this situation, there is a growing interest in using cold storage to preserve genetic samples taken from animals threatened with extinction.

Just as egg-freezing is used to preserve human fertility for a later date, the cryogenic freezing of genetic material from animals could be important in reducing species extinctions.  Living cell banks – also known as cryobanks – could preserve genetic materials from animals that include skin cells, embryos, semen, and live tissues.  These materials could be cultured and used for various applications including DNA extraction, assisted reproduction, ensuring genetic diversity in animal populations, and potentially reintroducing species back into their natural habitats.

There is a facility called the Frozen Zoo at the San Diego Wildlife Alliance which has genetic material from 965 different species, including 5% of the vertebrates currently listed as threatened on the IUCN Red List.  Further sampling from zoos and aquariums could increase that representation to almost 17%.

Genetic samples of 50% of the species currently listed as extinct in the wild are already represented in the Frozen Zoo.  Further sampling from the zoological community could increase this number to 91%.  This could provide a critical lifeline for these species that are on the brink of extinction.  As wildlife populations continue to decline around the world, it is more critical than ever to collect and preserve genetic samples from threatened species.

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Cryo conservation – a cool solution to saving species from extinction

Photo, posted September 30, 2018, courtesy of Andy Morffew via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio

Saving The Sumatran Rhino | Earth Wise

January 2, 2023 By EarthWise Leave a Comment

The Sumatran rhinoceros is the smallest and most ancient rhino species and is the only surviving species with hair.  It is critically endangered.  Because of poaching and habitat destruction, there are fewer than 50 of them left in the wild and those are scattered in the rainforests of Sumatra and the Indonesian part of Borneo.  Mating encounters between surviving males and females are increasingly rare.

The last male Sumatran rhino in Malaysia died in 2019 but cell samples from that individual are the basis of an ambitious effort in bioengineering.

Researchers from the Max Delbruck Center in Germany are taking skin cells from the deceased rhino and turning them into stem cells.  The hope is to use these stem cells to derive egg and sperm cells to be the basis of assisted reproduction.  Fertilization would take place in a petri dish.  The resultant embryos would then be carried to term by surrogate rhino mothers.

The researchers have reported success generating induced pluripotent stem cells or IPS cells from the rhino skin samples.  IPS cells are able to divide indefinitely and can transform into any cell type in the body.

The next step is to try to cultivate primordial germ cells – the precursors of eggs and sperm.

This work is going on because it is increasingly difficult to preserve the Sumatran rhino population by gathering together remaining individuals in wildlife Reserves.  Females that have not been pregnant for a long time often become infertile because of cyst growth on their reproductive organs, and some are just too old to bear young.

It may take extraordinary efforts like these to save these animals from extinction.

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A second chance for the Sumatran rhino

Photo, posted April 30, 2008, courtesy of Willem V. Strien via Flickr.

Earth Wise is a production of WAMC Northeast Public Radio

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